Digital Melting point apparatus Calibration SOP

1.0  OBJECTIVE:

To lay down the calibration procedure of Melting point apparatus.

2.0  SCOPE:

This shall be applicable to the Melting point apparatus of Quality Control Instrument Laboratory.

3.0  RESPONSIBILITY:

3.1  Technical Assistant/ Helper.

3.2  Q.C Analyst.

4.0  ACCOUNTABILITY:

4.1  Manager-Quality Control.

5.0  MATERIAL AND EQUIPMENT:

5.1  Melting point apparatus.

5.2  Samples (Vanillin, Acetanilide, Benzoic acid, Phenacetin & Caffeine).

6.0  PROCEDURE:

6.1  Ensure that all the connections of the instrument are proper.

6.2  Switch ON the mains.

6.3  Make sure that the instrument is clean according to SOP.

6.4  Operate the Melting point apparatus according to SOP.

6.5  Check the melting point of the following reference standards:

(Vanillin, Acetanilide, Benzoic acid, Phenacetin & Caffeine).

6.6  Take the reference standards from lowest range to highest range at a time of calibration.

6.7  Record all the results in the calibration record as per annexure-1.

6.8  Record the result on the “Calibration Record”, “Calibration Log Book” & paste the “Calibration Status Sticker” on Melting point apparatus.

6.9  Acceptance criteria:

6.9.1        The melting point of reference substances should be within the standard range.

6.10    Frequency:

6.10.1    Once in a month.

6.11    Maintenance/ repair:

6.11.1    Report any discrepancy observed during calibration or operating the instrument to the dept. Head and notify the defect to utility dept. to rectify the defect. Affix “BREAKDOWN” label on the instrument till it get rectified.

7.0  REVISION LOG:

Revision No.	Effective Date	Reason
00		New SOP

8.0  REFERENCES:

8.1  Not Applicable.

9.0  ANNEXURES:

Annexure 1: Calibration report of Melting point apparatus.

Annexure: 1

Calibration report of Melting point apparatus.

Calibration date Date of last calibration done Next due for calibration INSTRUMENT DETAILS: Instrument name Instrument make Instrument identification no. OBSERVATIONS: Sr.# Reference standard Temperature Observed range Standard range Initial (Ti) Final (Tf) Tf - Ti 1. Vanillin 81oC-83oC 2. Acetanilide 114oC-116oC 3. Benzoic acid 121oC-123oC 4. Phenacetin 134oC-136oC 5. Caffeine 234oC-237oC Conclusion: Satisfactory/ Not satisfactory. Done by/date Checked by/date

10.0    ABBREVIATIONS:

Abbreviation	Expanded Form
SOP	Standard operating procedure
&	And
No.	Number
Ltd.	Limited
Q.C	Quality control
Q.A	Quality assurance
QCEB	Quality control equipment calibration
F	Format
Ti	Initial temperature
Tf	Final temperature
Temp.	Temperature
oC	Degree centigrade
Sr.#	Serial number