SOP For Sanitation Program

 SOP For sanitation program is described in this post which you can follow in the section of the Quality Assurance Department.

OBJECTIVE

This SOP has been established to describe the procedure for cleaning and sanitation of the plant. 

The purpose of this standard procedure is to detail the cleaning and sanitation program.

SCOPE

This SOP applies on all the departments at plant.

RESPONSIBILITY

Q.A Officer

Q.C Officer

Production Officer

ACCOUNTABILITY

Manager Quality Assurance

PROCEDURE

GENERAL CLEANING

For daily clearance of product wastes, chemicals, rejected materials or any other debris use poly bags for quick disposal. Disposal procedures for waste materials and debris should be recorded and maintained.

General cleaning of all areas and floors / walls of all departments should be carried out by using the vacuum cleaner, the wet mops and dusting cloths.

Cleaning of windows should be done with dusters and cleaning solutions daily.

All surfaces above 6’ height should be cleaned / dedusted daily after the normal working hours.

Cleaning should not be carried out if a contamination hazard could occur to “IN PROCESS MATERIALS” but if it is essential it should be conducted after stopping the processing/manufacturing.

The cleaning / sanitation of different areas including the furniture and fixture should be done as follows and if required the frequency can be increased on request.

Clean wash rooms sinks and surroundings, replenish soaps and Replace hand towels/ tissue rolls once in a day.

Cleaning materials to be used are:

Wet mops

Detergent solutions / liquid soaps (teapot, Vim etc.)

Vipers

Dusters

Scrubber / polisher / glass cleaner

Disinfectant solutions i.e. Dettol, Phenyl, Sodium Hypertonic if bleach is required.

Insecticides 

CARE OF CLEANING MATERIALS

Wet mops: The mop heads should be rinsed in clean water and then in disinfectant solution. After mopping, it should be thoroughly washed with plenty of water and put to stand on end to dry. This should be done immediately after use. 

Buckets should be thoroughly washed with Vim and detergent solution, and then turned upside down to drain.

If bleach (Sodium Hypertonic Solution) is to used for cleaning, it must not be left on floor having Vinyl or Formica coverings but should be immediately cleaned to avoid masks and fading of colors. Containers of bleach must not be placed on any surface other than the floor.

PRODUCTION

General Tablet Section

General Capsule Section

Psychotropic Tablet Section 

Cephalosporin Section (Dry Powder Suspension)

Cephalosporin Section (Dry Powder Injection)

Liquid Syrup Section

GENERAL AREA

COMPRESSION ROOM 

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bin will be emptied three times daily.

Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

HVAC ducts (inlets/outlets), Exhaust Fans will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week

COATING ROOM 

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bin will be emptied two times daily.

Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

HVAC ducts (inlets/outlets), Exhaust Fans will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

MANUFACTURING ROOM 

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bin will be emptied three times daily.

Mirror Doors, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning 

HVAC ducts (inlets/outlets), Exhaust Fans will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

CAPSULE FILLING

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bin will be emptied two times daily.

Mirror Door, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

A.C. will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

EQUIPMENT WASHROOM

Procedure for Daily Cleaning:

Floor will be cleaned with a viper two times in a day.

Floor will be wet mopped two times daily.

Door, Door Handles and Door Closer will be cleaned daily.

Procedure for Weekly Cleaning: 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

PACKING HALL (ORAL)

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four times daily.

Floor will be wet mopped four times daily.

Waste bin will be emptied four times daily.

Windows, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Furniture will be cleaned/ dedusted once in a day.

Procedure for Weekly Cleaning: 

Fans, A.C.’s, Exhaust Fans will be cleaned on weekly basis. 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Procedure for Quarterly Cleaning 

Furniture will be cleaned thoroughly with liquid soap & disinfectants.

BLISTERING ROOM

Procedure for daily cleaning:

Floors will be cleaned with a brush three times daily.

Floors will be wet mopped three times daily.

Waste bin will be emptied three times daily.

Mirror Door, Door Handles, Steel plates and door closer will be cleaned once in a day.

Procedure for weekly cleaning:

A.C.’s will be cleaned on weekly basis.

Switchboards and Tube light will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

STERILE AREA

Cephalosporin Area

Above-mentioned area IS subdivided into washing rooms, filling rooms, sealing rooms & adjacent areas (cool downs, buffers, sterile area gowning and degowning rooms)

Sterile area cleaning procedure is different as with other areas of Oral Section.

CLEANING, MOPING AND FUMIGATION OF STERILE AREA 

PROCEDURE

General cleaning is done in the whole sterile area twice a day.

Mop the whole sterile area except filling & change rooms with disinfectant. The disinfectant solutions are 70% IPA or 5% Phenol solution alternatively.

The cleaning of sterilizers & autoclave is done with distilled water & disinfectant solution internally using lint free duster.

The trolleys of sterilizers are also washed with distilled water.

Trays are washed with distilled water.

Fumigation is done in the vials washing area after every week using KMnO4 & Formalin solution.

DECARTONING ROOMS (VIALS)

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bin will be emptied three times daily.

Mirror Doors, Door Handles and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning 

HVAC ducts (inlets/outlets) will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

CORRIDORS ADJACENT TO STERILE AREAS

Procedure for Daily Cleaning

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bin will be emptied two times daily.

Mirror Doors, Door Handles and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning 

HVAC ducts (inlets/outlets), Exhaust Fans will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

OPTICAL CHECK

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four times daily.

Floor will be wet mopped four times daily.

Waste bins will be emptied four times daily.

Furniture will be cleaned/dedusted daily.

Procedure for Weekly Cleaning 

Fans and A.C.’s will be cleaned on weekly basis. 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Procedure for Quarterly Cleaning 

Furniture will be cleaned thoroughly with liquid soap & disinfectants

INPROCESS STORE OF INJECTABLES

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bins will be emptied two times daily.

Door, Door Handles and Door Closer will be cleaned once in a day.

Furniture will be cleaned/ dedusted once in a day.

Procedure for Weekly Cleaning: 

Exhaust Fans will be cleaned on weekly basis 

Switch Boards and Tube Lights will be cleaned on weekly basis.

PACKING HALL (INJECTABLES)

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four times daily.

Floor will be wet mopped four times daily.

Waste bins will be emptied four times daily.

Windows, Doors Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

Fans and A.C.’s will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Procedure for Quarterly cleaning: 

Furniture will be cleaned thoroughly with liquid soap & disinfectants

WAREHOUSE

Raw & Packing Store

Finished Goods Store 

Raw & Packing Store

MAIN STORAGE AREA

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bins will be emptied three times daily.

Windows, Mirror Doors, Doors Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning:

A.C.’s, Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

DISPENSING ROOMS

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Windows, Mirror Doors, Doors Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning 

A.C.’s, Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

NOTE: The Mop used in a Dispensing rooms will not be used anywhere else.

RAW MATERIAL STORE

Procedure for Daily Cleaning:

Floor will be cleaned three times in a day.

Floor will be wet mopped once a day.

Procedure for Weekly Cleaning:

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

SAMPLING BOOTH

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Mirror Doors, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning:

A.C.’s, Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

RECEIPT ROOM

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Procedure for Weekly Cleaning 

Switchboards and Tube Lights will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

FINISHED GOODS STORE

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bins will be emptied two times daily.

Windows, Doors, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

Fans, A.C.’s, Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Fridge and Deep freezers will be cleaned on weekly basis

QUALITY CONTROL / QUALITY ASSURANCE

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins/ Sharp bins will be emptied three times daily.

Windows, Doors, Doors Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning:

Fans, A.C.’s, Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Sharp bins will be cleaned on weekly basis.

Wooden furniture will be polished once in a week.

Procedure for Quarterly Cleaning:

Furniture will be cleaned thoroughly with liquid soap & disinfectants

NOTE: The Mop of Q.C / Q.A will not be used anywhere else

MICRO LAB

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins/Sharp bins will be emptied three times daily.

Windows, Doors, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning 

A.C.’s, Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Sharp bins will be cleaned on weekly basis.

NOTE: Mop of Micro lab will not be used anywhere else.

IN PROCESS LAB 

Procedure for Daily Cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bins /Sharp bins will be emptied three times daily.

Window, Door Handles, and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

Fan will be cleaned on weekly basis 

Switchboard and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week 

Sharp bins will be cleaned on weekly basis.

Procedure for Quarterly Cleaning:

Furniture will be cleaned thoroughly with liquid soap & disinfectants quarterly.

GENERAL AREAS

PRINTING SECTION 

Procedure for daily cleaning 

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Window, Doors, Door Handles, Steel plates and door closer will be cleaned once in a day.

Procedure for weekly cleaning:

Fan, will be cleaned on weekly basis.

Switchboards and Tube light will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

MAIN CORRIDOR

Main corridor will be cleaned four to five times in a day.

Floor will be wet mopped four to five times in a day.

WASHING ROOM CORRIDOR

Washing room corridor will be cleaned five times in a day.

NOTE: The mop used in main corridor and washing room corridor will not be use anywhere else.

OFFICES 

Procedure for daily cleaning:

Floor will be cleaned with a brush two times daily.

Floor will be wet mopped two times daily.

Waste bins will be emptied three times daily.

Window, Mirror Doors, Door Handles, Steal plates and door closer will be cleaned once in a day.

Procedure for weekly cleaning:

Fan, A.C.’s, exhaust fans will be cleaned on weekly basis.

Switchboards and Tube light will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Wooden furniture will be polished weekly.

WORKERS ENTRANCE CORRIDOR

Workers Entrance Corridor will be cleaned five times in a day.

WORKERS CHANGE ROOM (MALE)

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four to five times daily.

Floor will be wet mopped four to five times daily.

Waste bins will be emptied four to five times daily.

Doors, Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

NOTE: The mop used in male change room will not be used anywhere else.

WORKERS CHANGE ROOM (FEMALE)

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four to five times daily.

Floor will be wet mopped four to five times daily.

Waste bins will be emptied four to five times daily.

Doors, Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning:

Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

NOTE: The mop used in female change room will not be used anywhere else.

WORKERS CHANGE ROOM (NEW AREAS)

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four to five times daily.

Floor will be wet mopped four to five times daily.

Waste bins will be emptied four to five times daily.

Doors, Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning:

Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

NOTE: The mop used in workers change room will not be used anywhere else.

OFFICERS CHANGE ROOM (MALE)

Procedure for Daily Cleaning:

Officers change room (male) will be cleaned three times daily.

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Door, Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning: 

Exhaust Fans will be cleaned on weekly basis 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

NOTE: The mop used in officers change room (male) will not be used anywhere else.

EXECUTIVE CHANGE ROOM 

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Mirror Door, Door Handles, steel Plates and Door Closer will be cleaned once in a day

Procedure for Weekly Cleaning: 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

DEIONIZATION PLANT                                   

Procedure for Daily Cleaning:

Floor will be cleaned with a viper once in a day.

Floor will be wet mopped once in a day.

Procedure for monthly Cleaning:

Washing and polishing of floor once in a month.

MESS

Procedure for Daily Cleaning:

Floor will be cleaned with a brush four times daily.

Floor will be wet mopped four times daily.

Waste bins will be emptied four times daily.

Windows, Doors, Door Handles, steel Plates and Door Closer Once a day

Burners will be cleaned once a day.

Procedure for Weekly Cleaning:

Fans, Exhaust Fans will be cleaned on weekly basis. 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

Fridge and Deep freezers will be cleaned on weekly basis. 

Procedure for Quarterly Cleaning: 

Furniture will be cleaned thoroughly twice in a month with liquid soap & disinfectants.

RECEPTION 

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bin will be emptied three times daily.

Mirror Doors, Door Handles, steel Plates and Door Closer will be cleaned once in a day.

Procedure for Weekly Cleaning:

Fans will be cleaned on weekly basis. 

Switchboards and Tube Lights will be cleaned on weekly basis.

Walls will be cleaned on weekly basis.

Washing and polishing of floor once in a week.

ADMIN BLOCK

Procedure for Daily Cleaning:

Floor will be cleaned with a brush three times daily.

Floor will be wet mopped three times daily.

Waste bins will be emptied three times daily.

Washrooms will be cleaned three times daily.

Furniture will be cleaned /dedusted daily.

Procedure for Weekly Cleaning:

Fans, A.C’s and Exhaust fans will be cleaned on weekly basis. 

Switchboards and Tube Lights will be cleaned on weekly basis.

Washing of floor / walls once in a week.

Wooden furniture will be polished weekly.

Procedure for Quarterly Cleaning:

Furniture will be cleaned thoroughly with liquid soap & disinfectants.

WORKERS WASHROOMS 

Procedure for Daily Cleaning:

Floor, washbasins & walls will be cleaned with liquid detergent (Harpic) & powder detergent (Vim) three times daily.

Waste bins will be emptied three times daily.

Toilets will be cleaned with toilet cleaners/ acids once a day.

Walls will be washed once a day.

Procedure for Weekly Cleaning: 

Switchboards and tubes lights will be cleaned on weekly basis.

Exhaust fans will be cleaned on weekly basis. 

Drains of washrooms will be cleaned on weekly basis.

Procedure for Preparation of Mopping Liquid 

Take 05 liter of clean water and mix 20ml dettol with surf in it, shake it well and then use it for the mopping of the plant.

Floor polisher does polishing of the floor.